Tolvaptan CAS 150683-30-0 API High Quality Factory
Samar da masana'anta
Kyakkyawan inganci, Samar da Kasuwanci
Sunan Sinadari: Tolvaptan
Saukewa: 150683-30-0
| Suna | Tolvaptan |
| Sunan Sinadari | N-[4- (9-chloro-6-hydroxy-2-azabicyclo[5.4.0] undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide |
| Lambar CAS | 150683-30-0 |
| Lambar CAT | RF-API101 |
| Matsayin Hannun jari | A Hannun jari, Ma'aunin Samfura Har zuwa Ton |
| Tsarin kwayoyin halitta | Saukewa: C26H25ClN2O3 |
| Nauyin Kwayoyin Halitta | 448.94 |
| Alamar | Rufin Chemical |
| Abu | Ƙayyadaddun bayanai |
| Bayyanar | Fari zuwa Kashe-White Crystalline Foda |
| Hanyoyin Ganewa | IR, HPLC |
| Assay (HPLC) | 98.0 ~ 102.0% (a kan anhydrous tushen) |
| Matsayin narkewa | 219.0 ~ 222.0 ℃ |
| Asara akan bushewa | ≤0.50% |
| Ragowa akan Ignition | ≤0.10% |
| Tsaftace Guda Daya | ≤0.50% |
| Jimlar ƙazanta | ≤1.0% |
| Karfe masu nauyi | ≤20ppm |
| Ragowar Magani | Haɗu da ƙayyadaddun bayanai |
| Matsayin Gwaji | Matsayin Kasuwanci |
| Amfani | Matsakaicin Magunguna |
Kunshin: Bottle, Aluminum tsare jakar, 25kg / Kwali Drum, ko bisa ga abokin ciniki ta bukata.
Yanayin Ajiya:Ajiye a cikin kwantena da aka rufe a wuri mai sanyi da bushe;Kare daga haske da danshi.
Tolvaptan (CAS 150683-30-0), wanda kuma aka sani da OPC-41061, wani zaɓi ne, mai gasa arginine vasopressin antagonist 2 antagonist da aka yi amfani da shi don magance hyponatremia (ƙananan matakan sodium na jini) da ke hade da ciwon zuciya na zuciya, cirrhosis, da ciwon da bai dace ba. antidiuretic hormone (SIADH).Otsuka Pharmaceutical lasisi tolvaptan karkashin sunan kasuwanci Samsca bayan FDA ta amince da miyagun ƙwayoyi a watan Mayu 2009. Tolvaptan ya kuma nuna tasiri a kan polycystic koda cuta.A cikin gwaji na 2004, tolvaptan da aka gudanar tare da diuretics na gargajiya an lura da shi don ƙara yawan fitar da ruwa mai yawa da kuma inganta matakan sodium na jini a cikin marasa lafiya masu fama da ciwon zuciya ba tare da haifar da sakamako masu illa irin su hypotension (ƙananan jini) ko hypokalemia (rage matakan jini na potassium).Har ila yau, miyagun ƙwayoyi bai nuna wani tasiri ba akan aikin koda.
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